Videocase

PARKINSON’S DISEASE

Parkinson's disease (PD) is a chronic and progressive movement disorder, meaning that symptoms continue and worsen over time. The cause is unknown, and there are treatment options to manage its symptoms.
Parkinson's primarily affects neurons in an area of the brain called the substantia nigra. Some of these dying neurons produce dopamine, a chemical that sends messages to the part of the brain that controls movement and coordination. As PD progresses, the amount of dopamine produced in the brain decreases, leaving a person unable to control movement normally.1

Primary motor signs of Parkinson’s disease includes tremor of the hands, arms, legs, jaw and face; bradykinesia or slowness of movement; rigidity or stiffness of the limbs and trunk and postural instability or impaired balance and coordination.1

THE IDEA

Our challenge was to come up with a solution that could bring real help to these patients, while being easy to implement and fun to use. As we researched around some unmet needs in Parkinson’s we realized that, as much as drug therapy and neurological surgery are effective in reducing symptoms, one of them is very difficult to overcome: the so-called Parkinson’s gait2. Fortunately, it has been found that MUSIC with a RHYTHMIC PATTERN OF AUDITORY STIMULUS may help in Parkinson’s gait2. Music provides rhythm for patients to control their steps, releasing dopamine, a neurotransmitter associated with pleasure and motor control2-5. Science and music were already there – we just had to connect them. Welcome to PARKINSOUNDS®!

HOW IT WORKS

PARKINSOUNDS® is a free App that works based on a preset list of songs or through online connection with Spotify® playlists. Its operation mode is very simple and consists in 3 steps:
1. PARKINSOUNDS® helps patients find their ideal pace. Every patient has a walking speed and a built-in metronome helps finding it.
2. Once the ideal pace is saved, PARKINSOUNDS® automatically selects the songs that match that beat, either from a 30-song preset list or assembling a playlist of songs matching that beat on Spotify®.
3. PARKINSOUNDS® adds rhythmic auditory stimulus to the songs, in order to make them functional.
Important:TEVA recommends PARKINSOUNDS® to be used under supervision from a healthcare professional. This App does not replace drug treatments.

THIS IS ONLY THE BEGINNING!

TEVA PHARMACEUTICAL considers PARKINSOUNDS® as an innovative solution that aims to improve the quality of life and the independence of people who cope with neurological conditions.

References: 1. Parkinson' s Disease Foundation - http://www.pdf.org/about_pd. 16/03/2017 2. - Lopez, et al. Listenmee and Listenmee smartphone application: Synchronizing walking to rhythmic auditory cues to improve gait in Parkinson’s disease. Human Movement Science 37 (2014) 147–156). 3 - Aidin Ashoori, David M. Eagleman, Joseph Jankovic. Effects of auditory rhythm and music on gait disturbances in Parkinson’s disease. Front Neurol. 2015; 6: 234. 4 - Anna A. B., Piotr K., Elżbieta M., Przemysław B., Anna M.. Neurologic music therapy training for mobility and stability rehabilitation with Parkinson’s disease A Pilot Study. Front Hum Neurosci. 2015; 9: 710. 5 - Salimpoor et al., Anatomically distinct dopamine release during anticipation and experience of peak emotion to music. Nature Neuroscience Vol. 14 | Number 2 | February 2011.